D- Cloprostenol Sodium
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Product name: Deslorelin
Appearance: White powder
CAS No.:57773-65-6
Molecular Weight:1282.46
Molecular Formula:C64H83N17O12
Density: 1.48 g/cm3
Boiling Point: 1783.4°C at 760 mmHg
Flash Point: 1032.4 °C
Storage temp:20°C
Deslorelin acetate is an injectable gonadotropin releasing hormone super-agonist (GnRH agonist) also known as an LHRH agonist. It stops the production of sex hormones.
Deslorelin Acetate is marketed by Peptech with the brand name Ovuplant. It is currently approved for use in veterinary medicine and is used to induce ovulation in mares as part of theartificial insemination process. It is also used to stabilize high-risk pregnancies, mainly of livestock. Unlike other GnRH agonists, which are mainly used to inhibit luteinizing hormone andfollicle-stimulating hormone by their ultimate downregulation of the pituitary gland, Deslorelin is primarily used for the initial flare effect upon the pituitary, and its associated surge of LH secretion.
Index | Standard | Test result |
Appearance | White powder or almost white powder | Conforms |
Identity by HPLC | The retention is same with the reference substance | Conforms |
Amino Acid Composition | Glu:0.85~1.10 Pro:0.85~1.10 Leu:0.90~1.10 Tyr:0.85~1.10 His:0.85~1.10 Arg:0.85~1.10 Ser:Present Trp:Present | 0.95 1.03 1.01 0.99 1.00 0.98 0.9 determined |
Purity(By HPLC) | ≥98.0% | 99.01% |
Related Substance(By HPLC) | Total Impurities(%)≤2.0% Largest Single Impurity(%)≤0.5% | 0.99% 0.35% |
Acetate Content(By HPLC) | ≤12.0% | 9.58% |
Water Content(Karl Fischer) | ≤8.0% | 2.75% |
Peptide Content(N%) | ≥80.0% | 86.22% |
Bacterial Endotoxins | ≤70IU/mg | Comforms |
Assay(By anhydrous,acetic acid-free) | 95%~105% | 98.55% |
