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API and related Intermediates

    • Prostaglandin Latanoprost; 130209-82-4
Product information
NameAlprostadil
Structure Prostaglandin Latanoprost; 130209-82-4
Other nameLatanoprost; 130209-82-4
CAS NO.130209-82-4
Molecular FormulaC26H40O5
Molecular Weight432.601 g/mol





TEST

SPECIFICTIONS

TEST RESULTS

Appearance

Colorless or light yellow oil

Complies

Identification

IR of the sample should match with standard

Complies

RT of sample should match with standard in the

Related substances

Complies

Optical rotation

+31°~ +38°

+36°

Water content

2.0%

0.05%

Residue on ignition

0.5%

0.06%

Isopropyl diphenyl-

phosphorylpentanoate

 

0.1%

0.02%

Related Compound B

(15S-cis isomer)

0.5%

0.15%

Related Compound A

(5,6-trans isomer)

3.5%

0.21%

Related Compound E

(Latanoprost acid)

0.2%

N.D

Other max single impurity

0.1%

N.D

Total impurities

0.5%

N.D

Residue solvents

Acetone0.5%

N.D

Methanol0.3%

N.D

Toluene0.089%

N.D

Tetrahydrofuran0.072%

N.D

Ethyl acetate0.5%

0.09%

Dichloromethane0.06%

N.D

Assay

94%~102%

99.52%

Conclusion:

Complies with USP Standard 


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